The medicine management guidance support system comprises first prescription data storage means for storing patient prescription data, medicine information storage means for storing information on medicines, search means for searching information stored in the medicine information storage means for the medicine name on the basis of the features of the medicine which the patient carries, a determining means for determining the specific name of the medicine from the medicines hit by the searching means, and second prescription data storage means for storing the medicine as the patient previous prescription data when the determining means determines the specific medicine. The medicine management guidance support system further comprises checking means for checking the prescription data with the prescription data stored in the second prescription data storage means when the prescription data stored in the first prescription data storage means is ordered to a medicine department as a medicine preparing instruction and display means for displaying a message that there is a possibility to cause an event harmful to the patient if the result of checking by the checking means indicates the possibility.