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Fluorocarbon-linked peptide formulation
专利权人:
Jean Francois Thaburet;Bertrand Victor Gilbert Georges;Carlton Bradley Brown
发明人:
Carlton Bradley Brown,Bertrand Victor Gilbert Georges,Jean Francois Thaburet
申请号:
US13977265
公开号:
US09119811B2
申请日:
2011.12.30
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention provides an aqueous acidic formulation suitable for use as in the preparation of a pharmaceutically acceptable fluorocarbon-linked peptide formulation, which aqueous formulation comprises a first fluorocarbon-linked peptide, wherein: the peptide linked to the fluorocarbon is at least 20 amino acid residues long, comprises at least 50% hydrophobic amino acid residues and has an isoelectric point greater than or equal to 7; and the fluorocarbon-linked peptide is present in micelles.
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