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6-deoxy-6-thioether-amino acid cyclodextrin derivative and preparation method thereof
专利权人:
Youmao Qi
发明人:
Youmao Qi
申请号:
US13989794
公开号:
US10017584B2
申请日:
2011.11.21
申请国别(地区):
US
年份:
2018
代理人:
摘要:
6-deoxy-6-thioether-amino acid cyclodextrin derivative is obtained by condensing an amino acid derivative with halogenated cyclodextrin in presence of alkali. The 6-deoxy-6-thioether-amino acid cyclodextrin derivative includes 6-deoxysulfinyl-6-thioether-amino acid cyclodextrin derivative and 6-deoxysulfonyl-6-thioether-amino acid cyclodextrin derivative. Compounds provided are for reversing neuromuscular relaxation in patients and animals induced by muscular relaxants. The compounds are able to rapidly reverse and antagonize muscular relaxation induced by muscular relaxants and can be administrated in preparing a drug having an antagonist effect on muscular relaxation. The compounds have a general formula (I).
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中国工程科技知识中心
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