Patrick Duffy;Stefan H. I. Kappe;Urszula Krzych;Donald G. Heppner;Lawrence W. Bergman;Vladislav A. Malkov;Alice Tarun;Jason P. Wendler;Igor Bacik
发明人:
Patrick Duffy,Stefan H. I. Kappe,Urszula Krzych,Donald G. Heppner,Lawrence W. Bergman,Vladislav A. Malkov,Alice Tarun,Jason P. Wendler,Igor Bacik
申请号：
US12722439
公开号：
US08318183B2
申请日:
2010.03.11
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention provides isolated liver stage Plasmodium polypeptides comprising an amino acid sequence selected from the group consisting of SEQ ID NOs:1-48 and immunogenic derivatives thereof. The invention also provides isolated nucleic acid molecules encoding the liver stage Plasmodium polypeptides of the invention, compositions comprising one or more liver stage Plasmodium polypeptides of the invention, methods for inducing an immune response against the liver stage Plasmodium polypeptides, and methods for treating and diagnosing liver stage malaria.
