Referring to a pirrolo [1,4] benzodiazepine Derivative of formula (i), where the dashed line represents a Single Bond or double u and u h W and W are Oh, or, ocor, ocoor, among others R1, R2, R1 and R2 is H, alkyl, Hal C1 - C6, among others and are H OR N M is CH or ALK are alquileno ALK C1 - C6. R and R are C1 - C6 h, alkyl, aryl, etc. l is a Group - l1 - L2 - L1 is ALK - SOr - ALK - NR1 - ALK - S, among others L2 is CH2C (= o) - R - (ch2ch2o nr3) - ALK, among others R3 is H or c1-c6 alkyl R is an integer from 1 to 40 ZB is simple Link, or NH RB is H, C1 - C6 alkyl, cycloalkyl C3 - C7, among others.Preferred compounds are: 3 - (2 - [2 - [2 - (2 - (3 - [3 - (2 - {[2 - (2 - [bis - (S) - 2 - and - (e) - ylidene - 7 - Dimethoxy - tetrahydro - 1,2,3,11a pyrrolo [] [2,1c 1,4 Benzodiazepines ona] - 5 - 8 - - - - - iloximetil] pyridin-3 iloxi) - 4 - methyl - ethyl] amino} - 1,1 - dimethyl - 2.5 - - [etilsulfanil) pyrrolidin-1-yl] - propanoilamino} - ethoxy) - ethoxy] ethoxy] - etox (i) - N - hidroxisuccinimidilo propanoate, 3 - {2 - [2 - ({2 - [2 - (2 - {[2 - (2,6 - bis - [(S) - 2 - and - (e) - ylidene - 7 - Dimethoxy - tetrahydro - 1,2,3,11a pyrrolo [2,1c] [1,4] benzodiazepines - 5 - 8 - - One - iloximetil] pyridin-3 iloxi) - 4 - methyl - ethyl] amino} - 1,1 - dimethyl etilsulfanil - Acetylamino) ethoxy] ethoxy] - - - -) ethoxy] ethoxy] - N - hidroxisuccinimidilo propanoate, among others. These compounds are useful in the treatment of cancerREFERIDA A UN DERIVADO PIRROLO[1,4]BENZODIAZEPINA DE FORMULA (I), DONDE LA LINEA PUNTEADA REPRESENTA UN ENLACE SIMPLE O DOBLE U Y U SON H W Y W SON OH, OR, OCOR, OCOOR, ENTRE OTROS R1, R2, R1 Y R2 SON H, HAL, ALQUILO C1-C6, ENTRE OTROS Y E Y SON H U OR M ES CH O N ALK ALK SON ALQUILENO C1-C6 R Y R SON H, ALQUILO C1-C6, ARILO, ENTRE OTROS L ES UN GRUPO -L1-L2- L1 ES ALK-S, O-ALK-NR3-ALK-S, ENTRE OTROS L2 ES CH2C(=O)-NR3-(CH2CH2O)i-ALK, ENTRE OTROS R3 ES H O ALQUILO C1-C6 i ES UN ENTERO DE 1 A 40 Zb ES UNENLACE SIMPLE, O, NH Rb ES H, AL
