Use of the association of a selective and specific sinus node Ifcurrent inhibitor, more especially ivabradine orN-{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]-methyl}-3-(7,8-dimethoxy-1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-N-methyl-3-oxo-1-propanamine, and an agent that inhibits angiotensin-converting enzyme in obtaining medicaments intended for the treatment of heart failure, more especially heart failure having preserved systolic function.本發明係關於一種選擇性及特異性竇房結If電流抑制劑(更特定言之是指伊伐布雷定(ivabradine)或N-{[(7S)-3,4-二甲氧基二環[4.2.0]八-1,3,5-三烯-7-基]甲基}-3-(7,8-二甲氧基-1,2,4,5-四氫-3H-3-苯并氮呯-3-基)-N-甲基-3-側氧基-1-丙胺)與血管收縮素轉化酶抑制劑之結合,以獲得意欲治療心衰竭(更特定言之是指具有保留收縮功能之心衰竭)之藥物之用途。(無元件符號說明)
