A catheter guide assembly includes an extended working channel having aproximal portion adjacent a proximal end and a distal portion adjacent adistal end, theextended working channel having a lumen configured to enable translation of aninstrument therethrough. The extended working channel defines a radius formedon thedistal portion, wherein the distal portion of the extended working channel isformed of amaterial having a durometer rating sufficient such that deflection of thedistal portion islimited as the instrument is translated therethrough. The catheter guideassemblyincludes a control handle disposed at the proximal end of the extended workingchanneland operably coupled to the extended working channel, thereby enabling theextendedworking channel to advance and rotate.