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CREAM FOR THE ADMINISTRATION OF STEROIDS AND PROCESS FOR PREPARING THE SAME
专利权人:
INTERNATIONAL DRUG LICENSING
发明人:
RICHARD BRAEMER,JULIE GUERIN
申请号:
FR1557349
公开号:
FR3039399B1
申请日:
2015.07.31
申请国别(地区):
FR
年份:
2018
代理人:
摘要:
[0001] The invention relates to a process for preparing a water-in-oil emulsion [e / h] comprising the following steps: a) dissolving at least one active principle selected from the group of topical corticosteroids in an oily phase; b) dissolving at least one preservative free of chlorocresol, in an aqueous phase and the temperature is raised to the - addition of the temperature of reversal of phase; c) mixing and homogenization of the aqueous phase into the oily phase; d) rise in temperature of the mixture obtained at the top of the temperature of reversal of phase; e) cooling of the mixture, characterized in that: - the concentration of a preservative, expressed in percentage by mass relative to the total weight of the emulsion is less than 5%; the steps a) and (b) are made independently and in any order. [0002] The invention also relates to the emulsion obtained by the process according to the invention and its use.
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