NOLD MARCEL,NOLD CLAUDIA,ELLISDON ANDREW,WHISSTOCK JAMES
申请号：
IN201817000033
公开号：
IN201817000033A
申请日:
2018.01.01
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
This invention relates to polypeptides including variants of interleukin 37 (IL 37) and related therapeutics and compositions. The invention also relates to the use of the polypeptides and compositions in methods of treating inflammatory diseases or conditions. The present invention provides a monomeric anti inflammatory polypeptide comprising an amino acid sequence of an IL 37 monomer the amino acid sequence having a mutation or modification for preventing the anti inflammatory peptide from forming a homodimer.
