Byung Soo YOUN,Jae Min OH,Ju Young KIM,Myeung Su LEE
申请号：
US14834441
公开号：
US20170056367A1
申请日:
2015.08.25
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed is a pharmaceutical composition comprising eupatilin as an active ingredient for suppressing osteoclast differentiation, bone metastasis, and osteolysis and for preventing or treating periodontitis. Found to effectively inhibit the differentiation of osteoclast progenitors into osteoclasts and the fusion of mononucleated osteoclasts into multinucleated osteoclasts, and reduce the bone resorption of W multinucleated osteoclasts, Eupatilin is capable of effectively suppressing bone metastasis and osteolysis and may be used to prevent or treat periodontitis.
