The present invention relates to a pharmaceutical or nutraceutical composition comprising at least one inositol and resveratrol for use in the a) preventive and/or curative treatment in the metabolic disorders related to polycystic ovary syndrome b) treatment to reduce the symptoms associated with polycystic ovary syndrome such as menstrual cycle alterations and infertility and/or c) to decrease glucose, triglyceride and BMI levels in subjects with metabolic syndrome.