The differential diagnostic Cushing Cotards of the relevant corticotropin of improved method and system provide herein. Glucocorticoid receptor antagonists can be used in treatment method, and differentially influencing ratio has Cushing disease to dystopy Cushing Cotards the patient of ACTH and cortisol levels. Relevant hypercortisolism for otherness diagnosis corticotropin may include the patient for obtaining the pure and mild ACTH levels of baseline cortical, treatment is to patients glucocorticoid receptor antagonist (GRA), cortisol levels usually will be substantially improved according to an agreement, obtain post-processing and the patient of ACTH and cortisol levels, determine between the pure and mild ACTH of differential relationship baseline cortical and cortisol levels post-processing and ACTH it is horizontal and positive diagnosis is provided is based on differential relationship.
