A method, system, and article of manufacture are described for interactive control of multiple images with a high dynamic range that are displayed simultaneously. A medical image control engine provides several synchronous functional capabilities, which comprises an input module, a blending factor synchronization module, a window/level synchronization module, a display module, and an image storage. For window/level adjustment of two images in blended views, the blending factor synchronization module is configured to automatically link the activation of a window/level control of one image with a transparency blending factor that affects both images. For synchronization of window/level adjustments of two or more images, a window/level synchronization module is configured to automatically change window/level parameters of all remaining images when the user makes an adjustment to a window/level control of one image such that all images with updated window/level parameters are displayed simultaneously.
