A process for preparation of a biocompatible coating for bone implants comprises the steps ofextracting a base material from mammal bone, de- antigenating and possibly demineralizing the base material,to maintain the Type I native collagen content unaltered both in quantity and in quality, mechanically grinding the base material to obtain a powder and dispersing the powder in a liquid solvent selected from the group comprising water and salines to obtain a suspension adapted to be directly applied to a bone implant. A biocompatible coating for bone implants comprises a base material extracted from mammal bone which has undergone a process in which the base material grinded into powder is the solid component of a suspension that is applied by brush-painting or dipping to at least part of the surface of a bone implant, wherein said base material is conveniently de-antigenated to maintain the native Type I collagen content unaltered both in quantity and in quality with respect to that in the initial mammal bone extract.
