PROBLEM TO BE SOLVED: To provide excellent antitumor agents.SOLUTION: Provided is a parasympathetic nerve dominance and lymphocyte activation antitumor agent by upper gastrointestinal tract-mucosal absorption which contains an active ingredient containing choline or choline derivatives, and sugar or sugar derivatives and has a powdery or granular dosage form as well as which is used for applications in parasympathetic nerve dominance and lymphocyte activation, due to absorption from upper gastrointestinal tract mucosa by bringing in contact with saliva held in oral cavity for 30 seconds or more after oral ingestion, the active ingredient containing Ophiocordyceps sinensis extract derived from wild silkworm, propolis extract, Agaricus subrufescens extract, and Ganoderma lucidum extract a production method thereof an antitumor agent which is produced by a particular production method as well as an intraoral mucosal immunity activator.SELECTED DRAWING: NoneCOPYRIGHT: (C)2019,JPO&INPIT【課題】優れた抗腫瘍剤を提供すること。【解決手段】コリン又はコリン誘導体を含有する有効成分、及び、糖又は糖誘導体を含有し、剤型が粉末又は顆粒であり、経口摂取した後、口腔内に30秒以上留めておいて唾液と接触させることによって上部消化管の粘膜から吸収させて副交感神経を優位化及びリンパ球を活性化する用途に用いられる、上部消化管粘膜吸収による副交感神経優位化リンパ球活性化抗腫瘍剤であって、 該有効成分が、野蚕由来の冬虫夏草抽出物、プロポリス抽出物、アガリクス茸抽出物、及び、霊芝抽出物を含有することを特徴とする、上部消化管粘膜吸収による副交感神経優位化リンパ球活性化抗腫瘍剤、その製造方法、特定の製造方法で製造されるような抗腫瘍剤、並びに、口腔内粘膜免疫活性化剤。【選択図】なし
