A photoablation device (1) for photoablation of human or animal tissue (8) comprises: a laser source (2) being arranged to propagate a focused laser beam (21) with a beam waist, wherein a radius of the laser beam (21) increases from the beam waist into a direction of propagation (213) of the laser beam (21); an adjusting structure (41, 47) being arranged for adjusting an intensity of the laser beam (21); a position detector (6) for detecting a position of the laser source (2) in relation to the tissue (8); a positioning device (3) being arranged to move the laser source (2) in relation to the tissue (8); and a controller unit (4). The controller unit is arranged to define a photoablation zone of the laser beam (21), wherein the photoablation zone ends in a cutting face which is located at the beam waist or offset from the beam waist into the direction of propagation (213) of the laser beam (21), to adjust an intensity at the cutting face of the photoablation zone of the laser beam (21) by means of the adjusting structure (41, 47), and to move the laser beam (21) towards the tissue (8) by means of the positioning device (3), wherein the position of the laser source (2) detected by the position detector (6) is evaluated. The device according to the invention allows for conveniently controlling and determining the depth of the photoablation into the tissue by the movement of the laser beam towards the tissue. In particular, the depth can correspond to the movement of the laser beam towards the tissue. Furthermore, the photoablation energy or intensity can precisely be adjusted in accordance with the tissue. Like this, it is possible to take account of the individual properties of the tissue and to minimize heating of the tissue such that, e.g., carbonization of the tissue can be prevented.La présente invention concerne un dispositif de photoablation (1) permettant une photoablation d'un tissu humain ou animal (8) qui comprend : une source laser (2) agencée de sorte à p