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CORPS DE PROTÉINES RECOMBINANTES EN TANT QU'ADJUVANTS SPÉCIFIQUES D'IMMUNOGÈNES
专利权人:
Zera Intein Protein Solutions; S.L.
发明人:
申请号:
EP09740089.9
公开号:
EP2356133B1
申请日:
2009.10.09
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
An immunogen-specific is adjuvant for a vaccine or inoculum is disclosed. The adjuvant is comprised of particulate recombinant protein body-like assemblies (RPBLAs) that contain a recombinant fusion protein that contains two portions peptide-linked together. A first portion is a protein body-inducing sequence (PBIS) and a second portion is a T-cell stimulating immunogenic polypeptide whose sequence is that of a pathogenic polypeptide sequence present in or induced by a vaccine or inoculum. The adjuvant, when used as an inoculum in a host animal without a prior priming vaccination or inoculation, does not induce production of antibodies or T cell activation to the pathogenic sequence.
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