BELARDINELLI, LUIZ,GILLIES, HUNTER CAMPBELL,LIANG, FAQUAN,SHRYOCK, JOHN,YANG, SUYA
申请号:
CA2814518
公开号:
CA2814518C
申请日:
2011.10.14
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Provided is a use of a therapeutically effective amount of ambrisentan and atherapeutically effective amount of tadalafil for treating pulmonary arterialhypertension(PAH) in a human patient suffering from PAH, wherein the weight ratio ofambrisentan totadalafil is in a range from about 1:1 to about 1:10, and wherein ambrisentanhas the followingchemical formula:(see formula I), andtadalafil has the following chemical formula:(see formula II).