Robert M. Borzilleri,Brian E. Fink,Lalgudi S. Harikrishnan,Upender Velaparthi,Vishweshwaraiah Baligar,Hasibur Rahaman,Jayakumar Sankara Warrier
申请号:
US15754311
公开号:
US20180250303A1
申请日:
2016.08.23
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates generally to compounds of formula (I) that modulate the activity of TGFβR-1 and TGFβR-2, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.