CHEN, SAN YUAN,陈三元,陳三元,HU, SHANG HSIU,胡尚秀,LIU, DEAN MO,刘典谟,劉典謨,KUO, KUNTING,郭冠廷
申请号:
TW098124323
公开号:
TWI374751B
申请日:
2009.07.17
申请国别(地区):
TW
年份:
2012
代理人:
摘要:
Nanodevice and method for in vivo monitoring and release of drugs are provided. The disclosed nanodevice is characterized in having a drug-loaded nanosphere that is capable of releasing the encapsulated drugs upon magnetically stimulation. The nanodevice may also be used as a contrast agent for in vivo imaging and monitoring the concentration and distribution of the released drugs and/or active compounds injected separately into a target site of a subject.在此揭示活體內監控及釋放藥物的奈米裝置與方法。所揭示的奈米裝置特徵在於具有一裝載有藥物的奈米球,可透過磁性刺激而將其中的藥物釋出。也可將此奈米裝置當作一種顯影劑,於活體內造影並監控所釋出藥物或是單獨注入活體標的位置處之藥物的濃度與分佈情形。