A heat transfer system may include a heat transfer machine adapted to thermally couple to an heat transfer pack housed within an heat transfer device and transfer heat from the heat transfer pack using a power supply. The heat transfer device may include a housing and a heat transfer pack. The heat transfer pack may be adapted to thermally couple to the heat transfer machine, transfer heat to the heat transfer machine while thermally coupled to the heat transfer machine, and transfer heat from a mammals skin when the heat transfer device is in contact with the mammals skin and uncoupled from the heat transfer machine.