[6,6] and [6,7]-bicyclic GPR119 G protein-coupled receptor agonists

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专利权人:

Bristol-Myers Squibb Company

发明人:

John M. Fevig,Dean A. Wacker

申请号：

US13648436

公开号：

US08513265B2

申请日:

2012.10.10

申请国别(地区):

US

年份:

2013

代理人:

摘要：

Novel compounds are provided which are GPR119 G protein-coupled receptor modulators. GPR119 G protein-coupled receptor modulators are useful in treating, preventing, or slowing the progression of diseases requiring GPR119 G protein-coupled receptor modulator therapy. These novel compounds have the structure:or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein n1, n2, n3, n4, A, B, D, E, G, Y, Z, R1 and R2 are defined herein.

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