UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
发明人:
GIANNOUKAKIS, NICK,TRUCCO, MASSIMO M.
申请号：
CA2929310
公开号：
CA2929310A1
申请日:
2014.11.18
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention relates to tolerogenic mammalian dendritic cells (iDCs) and methods for the production of tolerogenic DCs. In addition, the present invention provides methods for administration of tolerogenic dendritic cells as well as particles containing oligonucleotides to mammalian subjects. Enhanced tolerogenicity in a host can be useful for treating inflammatory and autoimmune related diseases, such as type 1 diabetes.
