Anti-tumor agent and therapeutic effect prediction method for KRAS gene variant colorectal cancer patients

• 收藏
• 分享

专利权人:

大鵬薬品工業株式会社

发明人:

伊藤 雅信,岡部 博之

申请号：

JP2013529023

公开号：

JP5832541B2

申请日:

2012.08.15

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

This invention provides a method for predicting a therapeutic effect of chemotherapy that uses an antitumor agent comprising ±,±,±-trifluorothymidine and 5-chloro-6-(1-(2-iminopyrrolidinyl)methyl)uracil hydrochloride at a molar ratio of 1:0.5 on a colorectal cancer patient, the method comprising: (1) detecting the presence or absence of KRAS gene mutation in a biological sample obtained from the patient； and (2) predicting that the patient is likely to sufficiently respond to the chemotherapy, when KRAS gene mutation is detected in Step (1).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/