SHANGHAI HENGRUI PHARMACEUTICAL CO.,LTD.;JIANGSU HENGRUI MEDICINE CO. LTD.
发明人:
Yali WANG,Lianshan ZHANG,Jindong LIANG,Ang LI,Fanglong YANG
申请号:
US15113610
公开号:
US20170002090A1
申请日:
2015.01.22
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Ligand-cytotoxic drug conjugates, pharmaceutical compositions, preparation methods, and pharmaceutical uses thereof are provided. More specifically, a ligand-cytotoxic drug conjugate of general formula Pc-(X-Y-D)n is provided. The ligand-cytotoxic drug conjugate can be used to treat cancer via receptor modulation.