#$%^&*AU2015201906A120150507.pdf#####ABSTRACT Polypeptides and polynucleotides encoding same comprising at least one carboxyterminal peptide (CTP) of chorionic gonadotrophin attached to a carboxy terminus of a coagulation factor. Pharmaceutical compositions comprising the polypeptides 5 and polynucleotides of the invention and methods of using same are also disclosed.