A fluid transfer device or connection (2) comprises a fluid transfer tip that has a tapered friction fitting for a corresponding hub (10). A lever member (34) is pivotally mounted to move relative to the fluid transfer tip. A latch (46) such as a screw thread is mounted on the lever member (34) to engage the hub (10) and provide a positive connection e.g. screw fit in addition to the friction fitting. The lever member (34) may optionally be resiliently biased by a spring (40). The hub (10) is disconnected from the tip by pivoting the lever member (34) to release the positive connection with the hub (10) and to subsequently release the hub (10) from the friction fitting.