The invention relates to a method of imaging at least two chemical species using magnetic resonance imaging with signal separation for the two chemical species, the method comprising:- acquiring first and second echo data at different echo times resulting in a first and second acquired complex dataset,- modelling the first and second acquired dataset, said modelling comprising a spectral signal model of at least one of the chemical species,- identifying in the first and second acquired dataset the voxels for which the modelling yields a single, unambiguous mathematical solution for the signal separation, and- resolving the ambiguity for the voxels for which the modelling yields more than one mathematical solution, if any such voxels remain.
