The invention is a high-frequency electro medical device for pain therapy, physiotherapy and cell stimulation in general, comprising at least one high-frequency generator suited to be connected to a power supply network, at least one hand piece with application head suited to be connected to said generator. Said generator emits waves at two or more possible discrete and pre-established operation frequencies, according to the type of treatment to be carried out and to the patient, wherein said generator emits waves at 2 MHz, at 4 MHz and at 8 MHz.