LEVY, John, P.,REED, Rebecca, A.,MCNULTY, Joseph,JOHNSON, Robert, G., Jr.
申请号：
EP20140769552
公开号：
EP2967078(B1)
申请日:
2014.03.14
申请国别(地区):
欧洲专利局
年份:
2018
代理人:
摘要：
Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
