Jaspal S. Kang;Paul J. Maddon;William C. Olson;Norbert Schuelke;Jason Gardner;Dangshe Ma;Larry Green;Gerald P. Donovan
发明人:
Paul J. Maddon,Gerald P. Donovan,William C. Olson,Norbert Schuelke,Jason Gardner,Dangshe Ma,Jaspal S. Kang,Larry Green
申请号:
US12845686
公开号:
US08470330B2
申请日:
2010.07.28
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention includes stable multimeric, particularly dimeric, forms of PSMA protein, compositions and kits containing dimeric PSMA protein as well as methods of producing, purifying and using these compositions. Such methods include methods for eliciting or enhancing an immune response to cells expressing PSMA, including methods of producing antibodies to dimeric PSMA, as well as methods of treating cancer, such as prostate cancer.