prolonged release formulations for protein delivery to the eye and methods of preparing them

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专利权人:

ICON BIOSCIENCE, INC.;RAMSCOR, INC

发明人:

GLENN T. HUANG,LOUIS L. WOOD,VERNON G. WONG

申请号：

BR112013031685

公开号：

BR112013031685A2

申请日:

2012.06.11

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

The present invention provides for injectable pharmaceutical sustained release formulations for delivery of active agents, particularly therapeutic proteins, to the eye. The formulations are biocompatible, biodegradable sustained release formulations comprising low-solubility liquid excipients and relatively small amounts (less than about 10%) of biocompatible, biodegradable polymer such as PLA or PLGA polymers. A unit dose of 5 μL to 100 μL of the formulation provides for sustained release of the agent for at least 14 days.

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中国工程科技知识中心

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http://www.ckcest.cn/home/