The present disclosure provides a use of a collagen peptide for inducing expression of CCT gene, Parkin gene and MRPS5 gene, enhancing the mitochondrial activity of cells, promoting the skin fibroblast proliferation, and anti-aging.本發明提供一種膠原蛋白肽用於提升CCT基因、Parkin基因及MRPS5基因的表現量、提升細胞的粒線體活性、促進皮膚纖維母細胞增生及抗老化之用途。