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Triazanonane derivatives or pharmaceutically acceptable salt thereof for enhanced fluorine-18 labeling
专利权人:
Jae Min Jeong
发明人:
Jae Min Jeong,Dinesh Shetty,Dong Soo Lee,June-Key Chung,Myung Chul Lee
申请号:
US13983053
公开号:
US09012604B2
申请日:
2012.02.01
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to a triazanonane derivative indicated by the chemical formula 1 below, or a pharmaceutically acceptable salt thereof, and a method for preparing same, and the triazanonane derivative according to the present invention forms a complex with a metal-fluoride and displays an effect of increasing the labeling efficiency up to 78-90% when labeling F-18, thus enabling use in various radioactive medicine labeling(In the chemical formula 1, R1, R2, A. E. X, n and m are as defined in the present description.)
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