Systems and methods for computed tomography (CT) imaging using variable image quality factors or image capture settings in a single acquisition are disclosed. According to an aspect, a method includes using a CT system to capture CT image data of an object in a single acquisition. The method also includes adjusting one or more image quality factor or image capture settings of the CT system during capture of the CT image data of the object. Further, the method includes processing the CT image data for presentation based on the one or more image quality factor or image capture settings.
