Marsha A. Moses,Peng Guo,Jiang Yang,Debra Auguste,Daxing Liu
申请号：
US16494551
公开号：
US20200085972A1
申请日:
2018.03.16
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The disclosure provides liposomes (e.g., cancer-targeting liposomes) with ligands (e.g., EGFR ligands and ICAM-1 ligands) conjugated to liposome surfaces. In some embodiments, the molecular ratio of different ligands complement the relative molecular density (i.e., ratio) of overexpressed protein on the surface of a cell targeted by the liposome (e.g., cancer cell).
