Weiwen Jiang,Mallikarjuna R. Putta,Fu-Gang Zhu,Jillian M. DiMuzio,Lakshmi Bhagat,Sudhir Agrawal
申请号：
US15342054
公开号：
US20170145412A1
申请日:
2016.11.02
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention is directed to compounds, compositions, and methods useful for modulating NLRP3 mRNA or protein expression using gene silencing compounds comprising two or more single stranded antisense oligonucleotides that are linked through their 5′-ends to allow the presence of two or more accessible 3′-ends.
