Paul Ashton,Hong Guo,Leigh T. Canham,Dinesh Nadarassan
申请号：
US14855946
公开号：
US20160075776A1
申请日:
2015.09.16
申请国别(地区):
US
年份:
2016
代理人:
摘要：
This invention discloses reservoirs, such as implants for delivering therapeutic agents, particularly large molecules such as proteins and antibodies. The reservoirs may comprise a porous silicon-based carrier material impregnated with the therapeutic agent. The reservoir may be used in vitro or in vivo to maintain an equilibrium concentration of a therapeutic agent over an intended period of time such as over multiple days, weeks, months, or years. Additionally, the reservoir may be reloaded with additional therapeutic agent. These reservoirs may be used for treating or preventing conditions of a subject such as chronic diseases.
