COMPOSITIONS AND METHODS FOR INDUCING CONFORMATIONAL CHANGES IN CEREBLON OTHER E3 UBIQUITIN LIGASES

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专利权人:

Celgene Corporation

发明人:

CHAMBERLAIN, Philip,CATHERS, Brian, E.,LOPEZ-GIRAONA, Antonia

申请号：

EP15811480

公开号：

EP3160486A4

申请日:

2015.06.26

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Provided herein are compositions, therapeutic methods, screening methods, computational methods and biomarkers based upon the elucidation of the interaction among cereblon, its substrates and certain compounds or agents, including small molecules, peptides, and proteins.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/