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Use and composition of PDE4 modem for treatment, prevention and control of tuberculosis
专利权人:
CELGENE CORPORATION
发明人:
ZELDIS, JEROME B.,KAPLAN, GILLA
申请号:
PE2011001445
公开号:
PE20120580A1
申请日:
2010.02.09
申请国别(地区):
PE
年份:
2012
代理人:
摘要:
It refers to a compound composed of the following components: (1) PDE4 simulator, such as (+ - 2 - [1 - (3-etoxi-4-methoxinfel) - 2-methylenesulfoamide] - 4-acetamide oinderin-1, 3-diona, cyclopol-n - {2 - (1s) - 1 - (3-etoxinfel-4-methoxinfel) - 2 - (methylthio) ethyl] - 3-oxoindondil-4-il carboxamida, 1{2-[1-(3-etoxi-4-metoxi-fenil)-2-metansulfonil-ethil]-3-oxo-2,3-dihydro-1h-isoindol-4-il}-amida,methyester del acido 3-(3,4-dimetoxifenil)-3-(1-oxo-1,3-dihydroisominol-2-il)propionic,entre;(ii)1-anti-como-sulf,e.f.f.f.f.e.f.f.f.f.f.f.g.g.g.g.g.g.g.g. This is an effective way to treat, prevent and control tuberculosisSE REFIERE A UNA COMPOSICION QUE COMPRENDE: (I) UN MODULADOR DE PDE4 TALES COMO (+)-2-[1-(3-ETOXI-4-METOXIFENIL)-2-METILSULFONILETIL]-4-ACETILAMINOISOINDOLIN-1,3-DIONA, CICLOPROPIL-N-{2-[(1S)-1-(3-ETOXI-4-METOXIFENIL)-2-(METILSULFONIL) ETIL]-3-OXOISOINDONIL-4-IL}CARBOXAMIDA, ACIDO CICLOPROPANCARBOXILICO DE {2-[1-(3-ETOXI-4-METOXI-FENIL)-2-METANSULFONIL-ETIL]-3-OXO-2,3-DIHIDRO-1H-ISOINDOL-4-IL}-AMIDA, METILESTER DEL ACIDO 3-(3,4-DIMETOXIFENIL)-3-(1-OXO-1,3-DIHIDROISOINDOL-2-IL)PROPIONICO, ENTRE OTROS; (II) UN AGENTE ANTI-TUBERCULOSIS TALES COMO ISONIAZIDA, RIFAMPINA, ENTRE OTROS. DICHA COMPOSICION ES UTIL PARA TRATAR, PREVENIR Y CONTROLAR LA TUBERCULOSIS
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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