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METHOD OF INDUCING AN IMMUNE RESPONSE AGAINST HUMAN IMMUNODEFICIENCY VIRUS BY CO-LOCALIZED ADMINISTRATION OF VACCINE COMPONENTS
专利权人:
Janssen Vaccines &; Prevention B.V.
发明人:
Frank WEGMANN,Gijs HARDENBERG,Roland Christian ZAHN
申请号:
US16579193
公开号:
US20200093917A1
申请日:
2019.09.23
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Methods of inducing an immune response against human immunodeficiency virus (HIV) are described. In particular, methods of inducing an immune response against HIV by co-locally administering an immunogenically effective amount of an isolated HIV envelope (Env) polypeptide and an immunogenically effective amount of an adenovirus vector encoding an HIV antigen, e.g., Env antigen are described. The isolated HIV Env polypeptide and adenovirus vector can be administered in a single composition or in separate compositions, in which the composition or compositions do not contain an adjuvant.
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