PROBLEM TO BE SOLVED: To provide an AI-2 inhibitor that has activity of inhibiting AI-2 and is effective in preventing and treating dental caries or periodontal disease.SOLUTION: An AI-2 inhibitor includes pulegone as an active ingredient.COPYRIGHT: (C)2014,JPO&INPIT【課題】AI-2を阻害する活性を有し、齲蝕又は歯周病の予防及び治療等に有効な、AI-2の提供。【解決手段】プレゴンを有効成分とするAI-2阻害剤。【選択図】なし