ARNAUD LE TIRAN,THIERRY LE DIGUARHER,JEROME-BENOIT STARCK,JEAN-MICHEL HENLIN,ANNE-FRANCOISE GUILLOUZIC,GUILLAME DE NANTEUIL,OLIVIER GENESTE,JAMES EDWARD PAUL DAVIDSON,JAMES BROOKE MURRAY,I-JEN CHEN
申请号：
PH12014000194
公开号：
PH12014000194A1
申请日:
2014.07.08
申请国别(地区):
PH
年份:
2015
代理人:
摘要：
The present invention relates to new phosphate compounds, to a process for their preparation and to pharmaceutical compositions containing them. The compounds of the present invention are new and have very valuable pharmacological and pharmacokinetic characteristics for use in the field of apoptosis and cancerology. Apoptosis, or programmed cell death, is a physiological process that is crucial for embryonic development and maintenance of tissue homeostatis. In addition to being new, the compounds of the present invention have pharmacological and pharmacokinetic properties making it possible to use them in pathologies involving a defect in apoptosis, such as, for example, in the treatment of cancer, auto-immune diseases and diseases of the immune system.
