Ladner, Robert Charles,Ley, Arthur C.,Hirani, Shirish,Williams, Anthony,De Simoni, Maria Grazia,Bergamaschini, Luigi,Blair, Henry,Beck, Thomas
申请号：
AU2011218732
公开号：
AU2011218732B2
申请日:
2011.09.01
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
#$%^&*AU2011218732B220130704.pdf#####ABSTRACT Methods, kits and compositions are described that include a non-naturally occurring kallikrein inhibitor and an anti-thrombolytic agent, e.g., an anti-fibrinolytic agent, for preventing or reducing blood loss and/or ischemia, e.g., ischemia associated with perioperative blood loss and cerebral ischemia, the onset of systemic inflammatory response, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia or a focal brain ischemia, e.g., in patients subjected to invasive surgical procedures, especially procedures requiring cardiopulmonary bypass. Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient by administering a kalliekrein inhibitor.1/9 00 .2 00 >； 0) >； 0 ~0 cu C0 o) -i Ad c-' >；% CL CLC 0 0 mo.o <； Ca cu. ~ a 0) UE c0 C 4-io C O CO (U 4,0x c w C) 12) C....co
