DERIVES 1,2,4-OXADIAZOLE UTILISES COMME IMMUNOMODULATEURS

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专利权人:

AURIGENE DISCOVERY TECHNOLOGIES LIMITED

发明人:

SASIKUMAR, POTTAYIL GOVINDAN NAIR,RAMACHANDRA, MURALIDHARA,NAREMADDEPALLI, SEETHARAMAIAH SETTY SUDARSHAN

申请号：

CA2922607

公开号：

CA2922607A1

申请日:

2014.09.05

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

The present invention relates to 1,2,4-oxadiazole and 1,2,4-thiadiazole compounds as therapeutic agents capable of inhibiting the programmed cell death 1 (PD1) signaling pathway. The invention also refers to derivatives of the therapeutic agents. The invention also encompasses the use of the said therapeutic agents and 5 derivatives for treatment of disorders via immunopotentiation comprising inhibition of immunosuppressive signal induced due to PD-1, PD-L1, or PD-L2 and therapies using them.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/