The subject matter described herein is directed to sanitizing compositions comprising: i. an antimicrobial component comprising a mixture of a quaternary ammonium salt, e.g., benzalkonium chloride and/or benzethonium chloride, paraben and acetic acid in a ratio of about 1:0.8-1.3:1.6-2.5 (w:w:v); ii. a lower alkyl ketone; and iii. an emollient; and optionally, iv. a fragrance. Methods of using and making the compositions are described as well as articles of manufacture incorporating the compositions.