Samuel Weiss,Emeka Enwere,Linda Andersen,Christopher Gregg
申请号:
US13493514
公开号:
US08435949B2
申请日:
2012.06.11
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides a method of increasing neural stem cell numbers or neurogenesis by using a pheromone, a luteinizing hormone (LH) and/or a human chorionic gonadotrophin (hCG). The method can be practiced in vivo to obtain more neural stem cells in situ, which can in turn produce more neurons or glial cells to compensate for lost or dysfunctional neural cells. The method can also be practiced in vitro to produce a large number of neural stem cells in culture. The cultured stem cells can be used, for example, for transplantation treatment of patients or animals suffering from or suspected of having neurodegenerative diseases or conditions.