A ventriculostomy patch system is disclosed herein. The ventriculostomy patch system including a base-ring, and a window assembly. The base-ring includes a circular body, with the circular-body having an outer-surface, an inner-surface, a top-surface, and a bottom-surface. The bottom-surface includes a catheter-notch the catheter-notch is configured for removably retaining a ventriculostomy catheter. The base-ring further includes at least two dome-tabs, each of the at least two dome-tabs located upon the outer surface of the base-ring. Preferably, the base-ring is constructed from anti-microbial materials. The window assembly includes an external-ring and a window, where the window assembly is removably affixable to the top-surface of the base-ring.