Yanwen Fu,Gunnar F. Kaufmann,Heehyoung Lee,Tong Zhu,Henry Hongjun Ji
申请号：
US16455184
公开号：
US20190358336A1
申请日:
2019.06.27
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Provided herein are cell penetrating compounds having the Formula I:where, generally, each T is a thiol reactive group (e.g., a phosphorothioate), each L is a linker (e.g., a linear alkyl), and Y is a biologic (e.g., an antibody). Also provided are pharmaceutical compositions including the cell penetrating compounds, and methods of delivering the compound into a cell.
