The present invention relates to an Acai berry extract for improving blood circulation and alleviating hypertension and a method for preparing the same. The Acai berry extract for improving blood circulation and alleviating hypertension, according to the present invention, comprises the Acai berry extract which is made by mixing dried Acai berries and alcohol with a weight ratio of 1:12 to 1:8, extracting at 12-30°；C, and freeze-drying the extract； has effects of inhibiting lipid peroxide, antioxidant for DNA damages, inhibitory activities on angiotensin converting enzyme (ACE), and suppressing nitric oxide (NO) synthesis； and has effects of increasing nitric oxide synthase-1 (NOS-1), superoxide dismutase-2 (SOD-2), and superoxide dismutase-3 (SOD-3) protein expression, increasing nuclear factor erythroid 2-related factor 2 (Nrf-2) expression, and reducing activities of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-&kappa；B) transcription factor.본 발명은 혈액순환 및 고혈압에 개선효과를 가지는 아사이베리 추출물 및 그 제조방법에 관한 것으로, 본 발명에 따른 혈액순환 및 고혈압에 대한 개선효과를 가지는 아사이베리 추출물은 건조된 아사이베리(Acai berry) 및 알코올 1 : 12 내지 1 : 8 중량비로 혼합하여 12 내지 30℃에서 추출하고, 상기 추출물을 동결건조시킨 아사이베리 추출물을 포함하고, 지질 과산화 억제, DNA 손상에 대한 항산화, ACE(Angiotensin Converting Enzyme) 효소 저해활성, nitric oxide(NO)의 생성 억제 효과를 나타내고, NOS-1(Nitric oxide synthase-1), SOD-2(Superoxide dismutase-2) 및 SOD-3(Superoxide dismutase-3) 단백질 발현을 증가, Nrf-2(Nuclear factor erythroid 2-related factor 2)의 발현 증가 및 NF-κB(nuclear factor kappa-light-chain-enhancer of activated B cells)전사인자의 활성을 감소 효과를 동시에 나타내는 것이다.
